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What we cover

Longevity

This is the beat most exposed to overclaiming, which is exactly why it needs covering carefully. A great deal of what is sold as longevity medicine rests on evidence considerably thinner than the confidence with which it is described.

What this beat covers

The measures with genuine outcome data behind them, separated from the ones with a good story and a pretty dashboard. Cardiorespiratory fitness and simple functional measures have some of the strongest associations with mortality in the literature, and both are cheap. Neither is on a routine physical.

We also cover the commercial layer honestly. Biological age tests, panels sold direct to consumers, and subscription programmes all make claims of varying quality, and a reader deserves to know which is which before spending.

Where we are sceptical

A measurement is only useful if it changes a decision. A great many longevity metrics are interesting without being actionable, and interesting is not worth paying for on a recurring basis.

We apply the same test to everything in this beat: what would you do differently if this number came back badly, and is that thing something you could have done anyway?

The measures

What we write about in this area

VO2 max
Among the strongest associations with all-cause mortality in the literature, and rarely measured outside sports settings.
Grip strength and gait speed
Unglamorous, nearly free, and surprisingly predictive.
Sleep, measured rather than reported
A home study sees things a questionnaire about how rested you feel does not.
Biological age panels
We cover what they actually measure and how much weight the underlying evidence supports.

Questions we keep coming back to

  • Which longevity measures change a decision, and which are only interesting?
  • How much of the benefit attributed to programmes is the measurement, and how much is the attention?
  • What should a reader make of a biological age result that disagrees with everything else?

We work through these continuously. The Coastline Brief is where the answers land first.